Cancer with benign prostatic hyperplasia, ROLUL GANGLIOZIDELOR ÎN PATOLOGIA PROSTATICĂ.

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Conținutul

    Urology - Therapy Room Urologie — Diagnostic, Investigații și Tratament personalizat Prostate cancer benign prostatic hyperplasia, Paraziți ai pielii corpului uman Prostate cancer benign prostatic hyperplasia Prostate cancer benign prostatic hyperplasia Prostate cancer benign prostatic hyperplasia - fotobiennale.

    In each group of lesions with cribriform architecture benign, premalignant and malignant intraductal or infiltratingthere are situations in which histological classification of the lesion is difficult or impossible on routine stains.

    Author s : Nicolae, Ilinca; Ene, Corina-Daniela; Georgescu, Simona Roxana Abstract: Molecular pathology of benign prostatic hyperplasia is multifactorial and involves endocrine, biochemical, immunological interactions. The mechanisms involved in the onset and progression of benign prostatic hyperplasia are: infections, 50 years of age, hormones and neurotransmitters imbalances, inflammation, oxidative stress.

    The potential role of glycosylation in the pathogenesis of prostate disease has been neglected.

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    Cuvinte cheie hiperplazie benignă de prostată IRM multiparametrică cancer de prostată PI-RADS imagistică medicală Introduction Benign prostatic hyperplasia BPH is a histologic diagnosis characterized by proliferation of the prostatic cellular elements.

    Benign hyperplastic nodules are most commonly seen in the transition zone, but they can also protrude into the peripheral zone or even beyond the prostatic capsule, appearing as an exophitic pelvic mass or as a mass within the bladder 2.

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    Usually, there is a direct relationship between prostate enlargement and symptoms severity, although many patients with small prostates also present urinary obstruction, because of the strategically position of the adenoma, sitting right on the bladder outlet 2. The initial evaluation should asses the frequency and severity of symptoms by using the International Prostate Symptom Score IPSS 4 and it should also include a digital rectal examination and urinalysis.

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    Enlargement of the prostate associated with a palpable nodule and elevated PSA prostate specific antigen level requires imaging methods of diagnosis, such as transrectal ultrasonography which provides a more accurate assessment of prostate volume than digital rectal examination does 5 and MRI for the characterization of the prostatic tissue, due to its excellent contrast resolution.

    In this study we documented the profile of gangliosides in normal and pathological prostatic tissues together with normal prostate volume pathologic changes seen in the level of extracellular gangliosides in patients with prostate pathology.

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    Analysis of the data in the literature suggests that gangliosides may represent immunologic markers useful in the differential diagnosis between prostate cancer and benign prostatic hyperplasia.

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    Mai multe despre acest subiect.

    Scopul depistarii precoce a cancerului de prostata este identificarea cancerului intr-un moment in care tratamentul este cel mai probabil eficient. Riscul de deces din cauza cancerului de prostata este semnificativ in cazul tumorilor de grad moderat sau crescut.